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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
33.64
Human Site:
Y450
Identified Species:
52.86
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
Y450
K
K
R
K
K
V
L
Y
N
A
N
K
N
D
D
Chimpanzee
Pan troglodytes
XP_510014
764
85553
Y539
K
K
R
K
K
V
L
Y
N
A
N
K
N
D
D
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
Y449
K
K
R
K
K
V
L
Y
N
A
N
K
N
D
D
Dog
Lupus familis
XP_547862
675
77214
Y450
K
K
R
K
K
V
L
Y
N
A
N
K
N
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
Y450
K
K
R
K
K
V
L
Y
N
A
N
K
N
D
D
Rat
Rattus norvegicus
Q5U2Y3
576
65604
D392
K
R
K
L
L
M
S
D
T
Q
H
Y
G
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
Y450
K
K
R
K
K
V
L
Y
N
A
N
K
N
D
D
Chicken
Gallus gallus
Q5ZJ00
468
52501
L287
P
A
F
K
R
K
T
L
V
L
I
G
A
S
G
Frog
Xenopus laevis
NP_001085267
675
76810
Y450
K
K
R
K
K
V
L
Y
N
A
N
K
N
D
D
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
Y452
K
K
R
K
K
M
Q
Y
N
A
N
K
N
D
D
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
L286
P
A
F
K
R
K
T
L
V
L
I
G
A
P
G
Fruit Fly
Dros. melanogaster
Q24210
898
100893
K701
V
T
Y
E
E
V
V
K
V
P
V
G
D
P
N
Honey Bee
Apis mellifera
XP_393395
1033
115664
Y809
N
D
D
G
Y
P
H
Y
A
T
T
A
I
D
D
Nematode Worm
Caenorhab. elegans
P54936
961
108794
Y747
K
K
Y
Y
T
T
K
Y
L
Q
K
H
S
A
L
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
K747
N
K
K
K
K
K
K
K
N
M
Y
N
N
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
6.6
100
86.6
6.6
6.6
20
20
40
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
100
13.3
100
93.3
13.3
40
20
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
0
0
0
0
7
54
0
7
14
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
0
0
7
0
0
0
0
7
67
60
% D
% Glu:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
0
20
7
0
14
% G
% His:
0
0
0
0
0
0
7
0
0
0
7
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
14
0
7
0
0
% I
% Lys:
67
67
14
74
60
20
14
14
0
0
7
54
0
0
0
% K
% Leu:
0
0
0
7
7
0
47
14
7
14
0
0
0
0
7
% L
% Met:
0
0
0
0
0
14
0
0
0
7
0
0
0
0
0
% M
% Asn:
14
0
0
0
0
0
0
0
60
0
54
7
60
0
7
% N
% Pro:
14
0
0
0
0
7
0
0
0
7
0
0
0
14
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
14
0
0
0
0
7
% Q
% Arg:
0
7
54
0
14
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
0
0
0
0
0
7
7
0
% S
% Thr:
0
7
0
0
7
7
14
0
7
7
7
0
0
0
7
% T
% Val:
7
0
0
0
0
54
7
0
20
0
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
7
7
0
0
67
0
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _